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Heart Failure in Young Adults: Moving in the Wrong Direction

If mortality rates among younger Americans are any indication, we can’t claim to be winning the battle against heart failure--yet. Here are some observations on the complex and evolving situation.

Navigating the ‘Pill-Counter’ Heart Failure Patient


In HFrEF, Does Diet Matter?


Identifying Transthyretin Amyloidosis in Heart Failure Patients

Q&A: Robert J. Mentz, MD on Iron Repletion in Heart Failure

Dr. Mentz, chief of the Heart Failure Section at Duke University Medical Center, provides an update on the importance of checking for and managing iron deficiency in patients with heart failure to improve functional status and quality of life.
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Diagnosing Sleep Apnea in Severe Heart Failure and Heart Transplant Patients

Texas-based researchers have concluded that a home sleep apnea test is effective for diagnosing sleep apnea in patients with advanced heart failure or heart transplant who have a positive screening result on the STOP-Bang Sleep Disorder Survey.

Infections in Patients with Decompensated Heart Failure are Common—and Dire

These findings suggest that 1 in 4 patients admitted with primary heart failure will also be diagnosed with an infectious condition, which can lead to an increase in in-hospital mortality, longer length of stay, higher risk of acute kidney injury, and more costly hospitalizations.

Distinctive Mechanisms Lead to Heart Failure in Black Adults

The results of this study suggest that subclinical impairments in cardiovascular and non-CV organ function are differentially associated with risk of incident heart failure with reduced or preserved ejection fraction in Black adults.

Heart Failure with Reduced Ejection Fraction: When Septic Shock Hits

A new study found that septic shock patients who have heart failure with reduced ejection fraction were less likely to receive guideline-recommended intravenous fluids compared with patients with normal EF. How did that disparity affect clinical outcomes?

Acute HF: Guideline-Directed Medical Therapy After Hospitalization

Patients hospitalized with acute heart failure often fail to receive prescriptions for guideline-directed medical therapy at discharge. This pattern of underprescribing leaves patients open to increased mortality and decreased quality of life, say the authors of a new study.

Approaching the Patient with Heart Failure with Mildly Reduced Ejection Fraction


Getting at the Root Cause of HFpEF

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Is Heart Failure Risk Increased by Rural Residence?

We often associate rural America with better living: cleaner air, less traffic, and lower levels of stress, all of which should have a positive effect on health. But when it comes to heart failure, residents of rural areas do worse than city dwellers, according to the results of a federally funded study.

Is Long-Term Heart Failure Risk Reduced by Bariatric Surgery?

After bariatric surgery, improvements in ventricular structure and function, epicardial fat, VAT, and ventricular interaction were shown in this study from Mayo Clinic.

Frail Acute HF Patients May Benefit from Multidomain Physical Rehabilitation

A secondary analysis of the REHAB-HF trial data showed that frail elderly heart failure patients had a 2.6 times greater improvement in SPPB score when compared with prefrail patients at 3-month follow-up.

N-Terminal Pro-B-type Natriuretic Peptide: What You Need to Know

These findings underscore the importance of accounting for sex and race when using NT-proBNP to assess patients’ risk of heart failure or death.

Implantable Pulmonary Artery Pressure Monitoring for Heart Failure

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Patient Education in Heart Failure

You don't have to provide all of the scientific details, but describing the disease process conceptually can often be very important to HF patients, explains Dr. Desai, of Yale. (1:06)

Heart Disease Mortality: A Closer Examination of Overall Trends

Some encouraging, positive trends in heart disease management and mortality have been followed by a leveling off. What will it take to get things moving again in the right direction?

Severe Obesity and Heart Failure

The nonlinear relationship between obesity and reduced mortality risk in HF patients, known as the obesity paradox, does not necessarily extend to secondary outcomes, according to these investigators. They suggest that the BMI-based definition of obesity needs refinement.

Device Therapy in Heart Failure


In Heart Failure, Can Therapy be Scaled Back with Improved Ejection Fraction?

Improving HF Treatment After Hospital Discharge: Some Surprising Findings

Self-monitoring, adherence incentives, and remote monitoring data sent to EHRs have been successful in past studies of patients with HF. But in this study, the patients using these approaches were no less likely to be readmitted or die.

Optimal Treatment in Heart Failure: What Are the Barriers?

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Heart Failure Treatment Guidelines: Compromising on Dosage

According to Nihar Desai, MD, MPH, of Yale, moving away from traditional medicine sequencing is likely a necessary and benefitial paradigm shift. (1:16)

Heart Failure Treatment: Addressing Patient Adherence


Heart Failure with Iron Deficiency: Where Does Supplementation Fit in?


In Heart Failure, Determining the Best Sequence of Medications

Survival Outcomes of CRT: Does Adding a Defibrillator Make a Difference?

This question was the focus of a recent German study that examined survival outcomes among more than 3500 patients who underwent cardiac resynchronization therapy (CRT) with or without the addition of a defibrillator.
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Cutting Down on Sodium: A Worthwhile Endeavor?

That was the question at the core of an international study that compared a low-sodium diet to usual care in more than 800 adults from 6 countries. Here's what the research team learned.

Heart Failure and LVH Linked to Poor Hydration in Middle Age

These investigators analyzed data over 25 years from nearly 12,000 adults who were enrolled in the ARIC study when they were 45 to 66 years old to assess the role of poor hydration in HF and LVH.

Kidney Disease and Heart Failure: A Troublesome Relationship

The presence of acute kidney injury (AKI) and chronic kidney disease (CKD) greatly increase the odds of being hospitalized for heart failure—and of death—within 6 months following an acute myocardial infarction (MI), according to the results of a new study.

Using Beta-Blockers to Lower Blood Pressure in Patients Without Heart Failure at Baseline: Worth the Risk?

A recent study found an association between use of beta-blockers to lower blood pressure and an increased incidence of heart failure in patients without heart failure at baseline.

Predicting Heart Failure Using PCP-HF

A recent study published in the American Journal of Cardiology assessed the accuracy and utility of the PCP-HF tool.

Non-diabetic Patients with HF May Benefit from Anti-hyperglycemic Meds

These investigators compared the impact of 3 distinct classes of glucose-lowering agents—metformin, SGLT2i, and GLP1-RA—on outcomes in nearly 3,000 non-diabetic HF patients.

Incident Heart Failure: Effects of Racial and Gender Differences

A large, prospective, multicenter study found that men, particularly Black men, have a heightened risk of poor systolic performance and HFrEF.